Williams: Clinical Dilemmas in Primary Liver Cancer

Part 1: Learning from a Worldwide Perspective.

• 1 Are patterns and prevalence changing? (Hashem B. El-Serag).
• 2 Why is the tumour different in Africa? (Nimzing G. Ladep).
• 3 Control by vaccination: Asian and Taiwan experience (Jia-Horng Kao).
• 4 The view from the UK (Shahid A. Khan, Mireille B. Toledano, Abigail Zabron, Mehtan Ahmed, and Simon D. Taylor-Robinson).
• 5 The view from the United States (Hitoshi Maruyama and Arun J. Sanyal).
• 6 New challenges of NAFLD and HIV epidemics (Quentin M. Anstee and Janice Main).

Part 2: Influence of Tumour Characteristics.

• 7 Controversies in Pathology (Tania Roskams).
• 8 Not to forget the unusual tumour (Bernard C. Portmann).
• 9 What can be learned from molecular diagnostic techniques and genetic signatures? (Tariq Moatter and Saeed Hamid).

Part 3: Complexities of Patient Assessment and Scoring Systems.

• 10 Looking after the liver as well as the tumour (Roger Williams).
• 11 Comparative performances of staging systems for hepatocellular cancer: Early HCC considerations (Peter D. Peng, Timothy M. Pawlik).
• 12 Rival scoring systems: Do they offer more? (Angelo Sangiovanni and Massimo Colombo).
• 13 Is it possible to detect early lesions effectively? (Ryota Masuzaki and Masao Omata).
• 14 What is the value of country based surveillance programmes? (Peter Ott).

Part 4: Choice of Radiological Diagnostic Technique.

• 15 Computed tomography or magnetic resonance imaging for the diagnosis of hepatocellular carcinoma (Wladyslaw Gedroyc).
• 16 Is Microbubble ultrasound useful? (Adrian Lim).
• 17 Value of PET scanning (Tara Barwick, Imene Zerizer, and Adil Al-Nahhas).

Part 5: Can Treatment be Tailored to the Patient?

• 18 Who could benefit from chemoembolisation? (Gisèle N'Kontchou, Olivier Seror, and Michel Beaugrand).
• 19 Are drug eluting beads (DEB) worth using? (C. N. Hacking and Pradesh Kumar).
• 20 What's the future of image-guided radiofrequency ablation for hepatocellular carcinoma? (Riccardo Lencioni).
• 21 Alternative ablation techniques for hepatocellular carcinoma (John Karani).
• 22 Justification for Sorafenib and chemotherapy (Philip J. Johnson).
• 23 When to consider surgery? (Emmanuel Melloul, Mickaël Lesurtel, and Pierre-Alain Clavien).
• 24 Transplant considerations (Myron Schwartz).

Part 6: What Does the Future Hold?

• 25 Dipstick markers for diagnosis: Feasible or not? (Mohamed I. F. Shariff and Simon D. Taylor-Robinson).
• 26 Targeted gene therapy for hepatocellular carcinoma (HCC): A reality? (Christopher Binny, Marco Della Peruta, and Amit C. Nathwani).
• 27 Is immune modulation a possibility? (Tim F. Greten and Firouzeh Korangy).
• 28 Systemic therapy for hepatocellular carcinoma: Future directions (Daniel H. Palmer, Matthew Cramp).

 

Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients – in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide.

Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.

Product Details

• Paperback: 244 pages
• Publisher: Wiley; 1 edition (February 21, 2012)
• Language: English
• ISBN-10: 0470657979
• ISBN-13: 978-0470657973

List Price: $84.95 

 

Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary Care

Hepatocellular carcinoma (HCC) is a major cause of cancer mortality worldwide. This tumor, which is a major health problem worldwide, has stimulated the energy of several disciplines. The liver is a massive and complex organ requiring an excellent knowledge of its anatomy and physiology, with an exquisite comprehension of its impact on cardiovascular, pulmonary, and renal function. Because early detection is rare, the overall prognosis is generally poor. Understanding of the etiology, epidemiology, pathophysiology, molecular biology, and clinical features of HCC is important in providing optimal patient care. In addition, understanding of the limitations of our current knowledge and therapeutic capabilities is essential in order to guide future research efforts. Management of patients with HCC is necessarily a multidisciplinary effort which involves the skill of radiologists, pathologists, gastroenterologists, anesthesiologists, surgeons, medical oncologists, radiation oncologists, nurses, and other health professionals.
Initially, the treatment of HCC was limited to surgical approaches with liver resection being the only option with curative intent. The development of HCC in chronic liver disease was associated with a high risk of technical difficulties and a high morbidity/mortality rate. This has challenged liver surgeons to improve their knowledge regarding liver anatomy, assessment of liver function, use of intraoperative imaging, tolerance of vascular clamping, and better anticipation of postoperative liver recovery. As shown in several chapters of this book, progress in liver surgery for HCC has expanded its development, yielding a true specialty. Imaging of liver parenchyma was motivated by two different goals including an efficient screening along with an accurate evaluation of the tumor in a background of abnormal parenchyma.

Pathology of Hepatocellular Carcinoma

Pathology of Hepatocellular Carcinoma by Masamichi Kojiro covers the vast advances made in clinical diagnosis aiding earlier detection, while addressing the recent progress made in treatment of HCC to enable successful therapy.
It reviews the full range of pathological information of HCC based on the study of surgical cases and biopsy materials, along with images, to help compare findings that may be encountered by pathologists.
The developments in imaging have also led to the identification of equivocal small nodular lesions suggestive of premalignant lesions or early-stage HCC. These present a diagnostic and therapeutic challenge for both pathologists and clinicians. This text makes special reference to developments in detection of early-stage HCC and premalignant lesions which can increase effective treatment.

About the Author
Masamichi Kojiro, M.D. Department of Pathology, Kurume University School of Medicine, Kurume, Japan is one of the leading hepatic pathologists in the world. He has worked in the US at Massachusetts General Hospital. He is a member of the Board of Directors of the Japanese Society for Hepatology, former Associate Editor for the Journal of Hepatology (EASL), and served as Secretary-General for APASL from 2000-2002.

Book Details

• Hardcover: 184 pages
  
• Publisher: Wiley-Blackwell; 1 edition (October 6, 2006)
  
• Language: English
  
• ISBN-10: 1405139080
  
• ISBN-13: 9781405139083
  
• Dimensions: 9.8 x 7.3 x 0.6 inches
  
• List Price: $134.95
  

Hepatocellular Carcinoma - the most up-to-date knowledge

Hepatocellular Carcinoma by W. Y. Lau is a compendium of papers written by an international team of world-renowned experts, who cover topics in their respective areas of expertise. Presenting the most up-to-date knowledge of hepatocellular carcinoma, it covers all topics -- including those more controversial ones -- in this rapidly advancing field, from epidemiology to prevention, from molecular biology to gross pathology, from screening to atypical presentation, from diagnosis to treatment, and from assessment to choice of appropriate treatment. This volume is therefore an important contribution to the field of hepatocellular carcinoma.

Contents:

• Epidemiology
  
• Assessment of Liver Function
  
• Prevention
  
• Screening
  
• Tumor Markers
  
• Imaging
  
• Pathology
  
• Molecular Aspects
  
• Staging
  
• Selection of Patients for Liver Resection
  
• Intraoperative Ultrasound
  
• Intrahepatic Glissonian Approach
  
• Laparoscopic Liver Resection
  
• Techniques of Liver Transection
  
• Cryosurgery
  
• Local Ablative Therapy
  
• Systemic Chemotherapy
  
• Palliative Care
  
• and other papers
  

Book Details

• Hardcover: 864 pages
  
• Publisher: World Scientific Publishing Company; 1 edition (January 3, 2008)
  
• Language: English
  
• ISBN-10: 9812707999
  
• ISBN-13: 9789812707994
  
• Dimensions: 9.1 x 6.1 x 1.7 inches
  
• List Price: $310.00
  
• Amazon.com Price: $226.30
  
• You Save: $83.70 (27%)
  

Liver Cancer: New Research (Horizons in Cancer Research)

Liver Cancer: New Research (Horizons in Cancer Research) by Felix Lee presents the latest new research developments from around the world in the field of liver cancer.

Table of Contents

• Preface
  
• Malignant Epithelial Liver Tumours in Children, Adolescents, and Adults: Molecular Pathways of Cancerogenesis, Growth, and Spread
  
• Tumour Biology of Colorectal Liver Metastases
  
• Colorectal Cancer Liver Metastases: Destruction or Resection?
  
• Strategies for Inferior Phrenic Arteriography and Transcatheter Arterial Chemoembolisation in Patients with Hepatocellular Carcinoma
  
• MDM-2 Over-Expression in Hepatitis B x Antigen Positive Hepatocellular Carcinoma
  
• Understanding Mechanisms of Hepatocarcinogenicity of the Breast Cancer Drug Tamoxifen at the Molecular Level: Relative Risks to Women versus Rodents
  
• Immunotherapy in Metastic Liver Disease
  
• Cancer Surveillance Following Orthotopic Liver Transplantation
  
• Angiogenesis Related Factore in Hepatocellular Carcinoma and Anti-Angiogenesis Therapy
  
• Research on Angigenesis in Liver Cancer and Its Clinical Implications
  
• Index
  

Book Details

• Hardcover: 266 pages
  
• Publisher: Nova Biomedical Books; 1 edition (March 30, 2006)
  
• Language: English
  
• ISBN-10: 1594541825
  
• ISBN-13: 9781594541827
  
• Dimensions: 10.2 x 7.2 x 0.9 inches
  
• List Price: $110.00
  

100 Questions and Answers About Liver Cancer

• Title: 100 Q & A About Liver Cancer
• Author: Ghassan K. Abou-Alfa
• List Price: $16.95
• Amazon.com Price: $11.53
• You Save: $5.42 (32%)
• Paperback: 160 pages
• Publisher: Jones and Bartlett Publishers, Inc. (August 16, 2005)
• Language: English
• ISBN-10: 0763747548
• ISBN-13: 978-0763747541
• Book Dimensions: 8.7 x 5.8 x 0.3 inches

Written by two prominent physicians at Memorial Sloan - Kettering Cancer Center and filled with insider advice from actual patients, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease.