This multi-authored textbook compiles recent scientific advances in brain-tumor biology. In the past 10 to 15 years, there has been an explosion of information regarding the genesis and pathological classification of and new treatments for brain tumors. The main focus of this book is the gliomas, but it also deals with other primary brain tumors, such as meningiomas, as well as brain metastases. The editor has called on a notable group of authors who are widely recognized as experts and investigators of the fundamental abnormalities that characterize malignant brain tumors.The book has three sections. The first focuses on epidemiology, biology, genetics, and pathology; the second describes mechanisms and genetic pathways involved in oncogenesis; and the final section reviews new therapeutics. There is considerable overlap of information, particularly between the first two sections, in describing the critical pathways that are disrupted in glioma. For example, the molecular characteristics that distinguish a primary from a secondary glioblastoma are discussed many times. Nevertheless, this repetition enables each chapter to stand alone, freeing the reader from having to refer to prior material to follow an author's line of thought.
This book contains a welcome compilation of the known genetic abnormalities in malignant gliomas and is an excellent reference with a good description of each abnormality. Furthermore, many authors discuss the interaction of multiple abnormalities and how the interaction affects the survival of malignant cells. The book also takes up the full spectrum of brain-tumor biology. Thus, there are chapters describing overall immune regulation, how it works in the brain, and how it could be harnessed for the treatment of brain tumors.
Book Details
This book contains a welcome compilation of the known genetic abnormalities in malignant gliomas and is an excellent reference with a good description of each abnormality. Furthermore, many authors discuss the interaction of multiple abnormalities and how the interaction affects the survival of malignant cells. The book also takes up the full spectrum of brain-tumor biology. Thus, there are chapters describing overall immune regulation, how it works in the brain, and how it could be harnessed for the treatment of brain tumors.
Book Details
- Title: Brain Tumors (Contemporary Cancer Research)
- Editor: Francis Ali-Osman
- Hardcover: 400 pages
- Publisher: Humana Press; 1 edition (October 2003)
- Language: English
- ISBN-10: 1588290425
- ISBN-13: 9781588290427
- Book Dimensions: 10.2 x 7.2 x 1 inches
- List Price: $150.00
- Amazon.com Price: $136.50
- You Save: $13.50 (9%)
