The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature.
The text is up-to-date and provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes. The Biology of Cancer provides insights into many aspects of immunology, developmental biology, and neurobiology.
The exceptional full-color art program contains many images published for the first time. The book is extensively illustrated with schematic drawings, micrographs, computer-generated models and graphs. The pieces were chosen to support and clarify the concepts, as well as to supply additional interest.
Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories, and for clinical professionals.
Contents
Chapter 1: The Biology and Genetics of Cells and Organisms
Chapter 2: The Nature of Cancer
Chapter 3: Tumor Viruses
Chapter 4: Cellular Oncogenes
Chapter 5: Growth Factors and Their Receptors
Chapter 6: Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer
Chapter 7: Tumor Suppressor Genes
Chapter 8: pRb and Control of the Cell Cycle Clock
Chapter 9: p53 and Apoptosis: Master Guardian and Executioner
Chapter 10: Eternal Life: Cell Immortalization and Tumorigenesis
Chapter 11: Multistep Tumorigenesis
Chapter 12: Maintenance of Genomic Integrity and the Development ofCancer
Chapter 13: Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis
Chapter 14: Moving Out: Invasion and Metastasis
Chapter 15: Crowd Control: Tumor Immunology and Immunotherapy
Chapter 16: The Rational Treatment of Cancer
Glossary
Abbreviations/Acronyms
Book Details
- Hardcover: 850 pages
- Publisher: Garland Science; 1 edition (June 9, 2006)
- Language: English
- ISBN-10: 0815340788
- ISBN-13: 9780815340782
- Dimensions: 11.2 x 8.8 x 1.3 inches