Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Acute Promyelocytic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy (Current Topics in Microbiology and Immunology) by Pier Paolo Pandolfi and Peter K. Vogt is meant to summarize some of the most recent progress made in elucidating the pathogenesis of Acute Promyelocytic Leukemia (APL) and in the treatment of this form of leukemia. It is also meant to celebrate one of the most successful accomplishments in cancer research and contemporary biomedical research. APL was in fact regarded as an almost invariably fatal disease just a decade ago, while it is now considered a curable leukemia - if not cured - in many advanced cancer centers in the world. APL is perhaps the most compelling exmple to date of what could be done and will be done in the years to come in the combat and defeat of the cancer plague if appropriate ressources are made available to the scientific commnunity. This tremendous progress in APL research and treatment has been made possible through a number of seminal discoveries and by the concerted efforts of many labs worldwide that have raced and competed with each other, but also interacted and cooperated, to reach this remarkable goal. Many of these groups and investigators have contributed to this dedicated volume.

Book Details
  • Hardcover: 276 pages
  • Publisher: Springer; 1 edition (February 1, 2007)
  • Language: English
  • ISBN-10: 3540345922
  • ISBN-13: 9783540345923
  • Product Dimensions: 9.4 x 6.3 x 0.6 inches
  • List Price: $129.00
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