Checkpoint Responses in Cancer Therapy (Cancer Drug Discovery and Development) by Wei Dai summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs.This book distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases.
Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.
Product Details
- Hardcover: 314 pages
- Publisher: Humana Press; 1 edition (June 6, 2008)
- Language: English
- ISBN-10: 1588299309
- ISBN-13: 9781588299307
- Product Dimensions: 9.2 x 6 x 0.8 inches