The Cancer Degradome: Proteases and Cancer Biology will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how the degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to targeting proteolysis for therapy.
Product Details
- Hardcover: 1000 pages
- Publisher: Springer; 1 edition (September 19, 2008)
- Language: English
- ISBN-10: 0387690565
- ISBN-13: 978-0387690568
- Product Dimensions: 9.3 x 6.4 x 1.9 inches