Myeloma Bone Disease (Current Clinical Oncology)

This state-of-the-art book presents the forefront in the science and clinical management of myeloma bone disease.  Assembling the work of the world's premier thought leaders, this book begins with sections on clinical presentation, imaging, and biochemical markers and then goes on to discuss radiation, surgical, and medical therapies.
Specific chapters are devoted to bisphosphonates and novel therapeutic agents, such as RANKL inhibitors, Wnt signaling inhibitors, and IMiDs.  The mechanisms of osteoclast activation and osteoblast suppression in multiple myeloma are also explored.
Myeloma Bone Disease is a valuable resource for medical, surgical, and radiation oncologists and cancer researchers.

Contents 
1. Clinical presentation of myeloma bone disease (MBD)
2. Imaging of myeloma bone disease
3. Bone Markers in MBD
4. Radiation therapy for MBD
5. Surgical treatment (kyphoplasty, vertebroplasty and standard surgery)
6. Pathophysiology of MBD
7. Osteoclast activation in MBD
8. Osteoblast Suppression in MBD
9. Animal models of MBD
10. Bisphopsphonate treatment of MBD
11. Osteonecrosis of the jaw in myeloma
12. Novel therapies for MBD (Denosumab, velcade and imids)

Book Details

• Hardcover: 252 pages
• Publisher: Humana Press; 1st edition (May 4, 2010)
• Language: English
• ISBN-10: 1607615533
• ISBN-13: 978-1607615538
• Product Dimensions: 9.3 x 6.3 x 0.8 inches 

List Price: $219.00

Tags: Bone Cancer, Myeloma